Ocular Toxicity Of Ethambutol

Ocular toxicity of ethambutol. Goal: To assessment the literature on ocular toxicity of ethambutol--its background, clinical presentation, toxicity traits, management, monitoring, and preventive measures. OR ocular) AND (adverse OR toxic). Knowledge EXTRACTION: All information was collected and analysed by authors. Data SYNTHESIS: Ethambutol hydrochloride is a generally used first-line anti-tuberculous agent. Though uncommon, ocular toxicity in the form of optic neuritis (most commonly retrobulbar neuritis) has been well documented since its first use in the 1960s. Classically described as dose- and duration-associated and reversible on therapy discontinuation, reversibility of optic neuritis remains controversial. International guidelines on prevention. Early detection of ethambutol-induced ocular toxicity have been revealed. Nonetheless, opinion of the clinical effectiveness of normal imaginative and prescient assessments to enable early detection of toxicity is divided. CONCLUSIONS: The course of ethambutol-induced ocular toxicity is unpredictable. Measures to ensure a high degree of awareness in medical workers. Patients of this potential hostile effect appear to be the most effective present preventive technique. Categorised by the World Health Organization as a spot with an intermediate tuberculosis burden and good well being infrastructure, Hong Kong is in an excellent position to examine the unanswered questions about ethambutol-induced ocular toxicity.

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